Sören Halldén’s logic of nonsense is one of the most well-known many-valued logics available in the literature. In this paper, we discuss Peter Woodruff’s as yet rather unexplored attempt to advance a version of such a logic built on the top of a constructive logical basis. We start by recalling the basics of Woodruff’s system and by bringing to light some of its notable features. We then go on to elaborate on some of the difficulties attached to it; on our (...) way to offer a possible solution to such difficulties, we discuss the relation between Woodruff’s system and two-dimensional semantics for many-valued logics, as developed by Hans Herzberger. (shrink)

This chapter describes the potential far‐reaching consequences of contemplative higher education for the fields of science and medicine.

Logical anti-exceptionalism is the view that logic is not special among the sciences. In particular, anti-exceptionalists claim that logical theory choice is effected on the same bases as any other theory choice procedure, i.e., by abduction, by weighting pros and cons of rival views, and by judging which theory scores best on a given set of parameters. In this paper, we first present the anti-exceptionalists favourite method for logical theory choice. After spotting on important features of the method, we discuss (...) how they lead to trouble when the subject matter of choice is logic itself. The major difficulty we find concerns the role of the logic employed to evaluate theory choice, or, more specifically, the role of the metalanguage employed to run the abductive method. When rival logical theories are being evaluated and compared, we argue, it is difficult not to beg some important questions; the metalanguage introduce biases difficult to avoid. These difficulties seem to be inherent to the method described. We suggest that they put some constraints on the scope of application of the method of abductive theory choice in logic and on the kind of disputes the anti-exceptionalist may plausibly expect to solve with it. We end the paper with some suggestions for how the anti-exceptionalist may address these issues on this front. (shrink)

The concept of supermatrix for social scientists was first introduced by Paul Horst. The main purpose of his book was to introduce this concept to social scientists, students, teachers and research workers who lacked mathematical training. This book introduces the concept of fuzzy super matrices and operations on them. The author has provided only those operations on fuzzy supermatrices that are essential for developing super fuzzy multi expert models. This book will be highly useful to social scientists who wish to (...) work with multi expert models. (shrink)

Smarandache in 2019 has generalized the algebraic structures to NeutroAlgebraic structures and AntiAlgebraic structures. In this paper, authors, for the first time, define the NeutroAlgebra of neutrosophic triplets group under usual+ and x, built using {Zn, x}, n a composite number, 5 < n < oo, which are not partial algebras. As idempotents in Zn alone are neutrals that contribute to neutrosophic triplets groups, we analyze them and build NeutroAlgebra of idempotents under usual + and x, which are not partial (...) algebras. We prove in this paper the existence theorem for NeutroAlgebra of neutrosophic triplet groups. This proves the neutrals assocaited with neutrosophic triplet groups in { Zn, X} under product is a NeutroAlgebra of triplets. We also prove the non-existence theorem of NeutroAlgebra for neutrosophic triplets in case of Zn when n = 2p, 3p and 4p (for some primes p). Several open problems are proposed. Further, the NeutroAlgebras of extended neutrosophic triplet groups have been obtained. (shrink)

In this paper, a modified form of Collatz conjecture for neutrosophic numbers n ∈ (Z U I) is defined. We see for any n ∈ (Z U I) the related sequence using the formula (3a + 1) + (3b + 1)I converges to any one of the 55 elements mentioned in this paper. Using the akin formula of Collatz conjecture viz. (3a- 1) + (3b -1)I the neutrosophic numbers converges to any one of the 55 elements mentioned with appropriate modifications. (...) Thus, it is conjectured that every n ∈ (Z U I) has a finite sequence which converges to any one of the 55 elements. (shrink)

In this book authors for the first time introduce the notion of super interval matrices using special intervals. The advantage of using super interval matrices is that one can build only one vector space using m × n interval matrices, but in case of super interval matrices we can have several such spaces depending on the partition on the interval matrix.

In this book authors for the first time introduce the notion of supermatrices of refined labels. Authors prove super row matrix of refined labels form a group under addition. However super row matrix of refined labels do not form a group under product; it only forms a semigroup under multiplication. In this book super column matrix of refined labels and m × n matrix of refined labels are introduced and studied.

In this book, for the first time, authors try to introduce the concept of linguistic variables as a continuum of linguistic terms/elements/words in par or similar to a real continuum. For instance, we have the linguistic variable, say the heights of people, then we place the heights in the linguistic continuum [shortest, tallest] unlike the real continuum (–∞, ∞) where both –∞ or +∞ is only a non-included symbols of the real continuum, but in case of the linguistic continuum we (...) generally include the ends or to be more mathematical say it is a closed interval, where shortest denotes the shortest height of a person, maybe the born infant who is very short from usual and the tallest will denote the tallest one usually very tall; however this linguistic continuum [shortest, tallest] in the real continuum will be the closed interval say [1 foot, 8 feet] or [1, 8] the measurement in terms of feet. So, the real interval is a subinterval with which we have associated the real continuum in terms of qualifying unit feet and inches in this case. (shrink)

In this book, the authors systematically define the new notion of linguistic graphs associated with a linguistic set of a linguistic variable. We can also define the notion of directed linguistic graphs and linguistic-weighted graphs. Chapter two discusses all types of linguistic graphs, linguistic dyads, linguistic triads, linguistic wheels, complete linguistic graphs, linguistic connected graphs, disconnected linguistic graphs, linguistic components of the graphs and so on. Further, we define the notion of linguistic subgraphs of a linguistic graph. However, like usual (...) graphs, we will not be able to arbitrarily connect any two linguistic words of a linguistic set associated with a linguistic variable. They can be related or adjacent depending on the linguistic variable associated with the linguistic set. This is an exceptional feature of a linguistic graph. (shrink)

The notion of linguistic geometry is defined in this book. It is pertinent to keep in the record that linguistic geometry differs from classical geometry. Many basic or fundamental concepts and notions of classical geometry are not true or extendable in the case of linguistic geometry. Hence, for simple illustration, facts like two distinct points in classical geometry always define a line passing through them; this is generally not true in linguistic geometry. Suppose we have two linguistic points as tall (...) and light we cannot connect them, or technically, there is no line between them. However, let's take, for instance, two linguistic points, tall and very short, associated with the linguistic variable height of a person. We have a directed line joining from the linguistic point very short to the linguistic point tall. In this case, it is important to note that the direction is essential when the linguistic variable is a person's height. The other way line, from tall to very short, has no meaning. So in linguistic geometry, in general, we may not have a linguistic line; granted, we have a line, but we may not have it in both directions; the line may be directed. The linguistic distance is very far. So, the linguistic line directed or otherwise exists if and only if they are comparable. Hence the very concept of extending the line infinitely does not exist. Likewise, we cannot say as in classical geometry; three noncollinear points determine the plane in linguistic geometry. Further, we do not have the notion of the linguistic area of well-defined figures like a triangle, quadrilateral or any polygon as in the case of classical geometry. The best part of linguistic geometry is that we can define the new notion of linguistic social information geometric networks analogous to social information networks. This will be a boon to non-mathematics researchers in socio-sciences in other fields where natural languages can replace mathematics. (shrink)

In this book, the authors introduce the linguistic set associated with a linguistic variable and the structure of matrices, which they define as linguistic matrices. The authors build linguistic matrices only for those linguistic variables which yield a linguistic continuum or an ordered linguistic set. This book is organised into three chapters. The first chapter is introductory, in which we introduce all the basic concepts of linguistic variables and the associated linguistic set to make this book self-contained. Chapter two introduces (...) linguistic matrices and develops basic properties associated with them, like types of matrices, transpose of matrices and diagonal matrices. Most of the properties enjoyed by real or complex matrices are satisfied by these linguistic matrices. Chapter three deals with operations on the linguistic matrices. (shrink)

This book extends the concept of linguistic coordinate geometry using linguistic planes or semi-linguistic planes. In the case of coordinate planes, we are always guaranteed of the distance between any two points in that plane. However, in the case of linguistic and semi-linguistic planes, we can not always determine the linguistic distance between any two points. This is the first limitation of linguistic planes and semi-linguistic planes.

Algebraic structures on linguistic sets associated with a linguistic variable are introduced. The linguistics with single closed binary operations are only semigroups and monoids. We describe the new notion of linguistic semirings, linguistic semifields, linguistic semivector spaces and linguistic semilinear algebras defined over linguistic semifields. We also define algebraic structures on linguistic subsets of a linguistic set associated with a linguistic variable. We define the notion of linguistic subset semigroups, linguistic subset monoids and their respective substructures. We also define as (...) in case of deals in classical semigroups, linguistic ideals in linguistic semigroups and linguistic monoids. This concept of linguistic ideals is extended to the case of linguistic subset semigroups and linguistic subset monoids. We also define linguistic substructures. (shrink)

The new notions of super column FRM model, super row FRM model and mixed super FRM model are introduced in this book. These three models are introduced specially to analyze the biased role of the print media on 27 percent reservation for the Other Backward Classes (OBCs) in educational institutions run by the Indian Central Government.

The systematic study of supermatrices and super linear algebra has been carried out in 2008. These new algebraic structures find their applications in fuzzy models, Leontief economic models and data-storage in computers.

In this book, the authors introduce the notion of Super linear algebra and super vector spaces using the definition of super matrices defined by Horst (1963). Many theorems on super linear algebra and its properties are proved. Some theorems are left as exercises for the reader. These new class of super linear algebras which can be thought of as a set of linear algebras, following a stipulated condition, will find applications in several fields using computers. The authors feel that such (...) a paradigm shift is essential in this computerized world. (shrink)

The new classes of super special codes are constructed in this book using the specially constructed super special vector spaces. These codes mainly use the super matrices. These codes can be realized as a special type of concatenated codes.

In this book, authors, for the first time, introduce the new notion of special subset linguistic topological spaces using linguistic square matrices. This book is organized into three chapters. Chapter One supplies the reader with the concept of ling set, ling variable, ling continuum, etc. Specific basic linguistic algebraic structures, like linguistic semigroup linguistic monoid, are introduced. Also, algebraic structures to linguistic square matrices are defined and described with examples. For the first time, non-commutative linguistic topological spaces are introduced. The (...) notion of a linguistic special subset of doubly non-commutative topological spaces of linguistic topological spaces is introduced in this book. (shrink)

This chapter argues that the general philosophy of science should learn metaphilosophical lessons from the case of metaphysical underdetermination, as it occurs in non-relativistic quantum mechanics. Section presents the traditional discussion of metaphysical underdetermination regarding the individuality and non-individuality of quantum particles. Section discusses three reactions to it found in the literature: eliminativism about individuality; conservatism about individuality; eliminativism about objects. Section wraps it all up with metametaphysical considerations regarding the epistemology of metaphysics of science.

Traditionally, being a realist about something means believing in the independent existence of that something. In this line of thought, a scientific realist is someone who believes in the objective existence of the entities postulated by our best scientific theories. In metaphysical terms, what does that mean? In ontological terms, i.e., in terms of what exists, scientific realism can be understood as involving the adoption of a scientifically informed ontology. But according to some philosophers, a realistic attitude must go beyond (...) ontology. The way in which this requirement has been understood involves providing a metaphysics for the entities postulated by science, that is, answering questions about the nature of what ontology admits to exist. We discuss how two fashionable approaches face the challenge of providing a metaphysics for science: a form of naturalism and the Viking/Toolbox approach. Finally, we present a third way, which adopts the best of both approaches: the meta-Popperian method, which focuses on discarding the wrong alternatives, or better saying, the metaphysical profiles incompatible with certain theories. We present the meta-Popperian method, a metametaphysical method capable of objectively assessing which metaphysical profiles are incompatible with certain scientific theories. For this, we will use quantum mechanics as a case study, presenting some previously obtained results. As our focus is on methodological questions about the relationship between metaphysics and science; with this method, we can see how science can be used to avoid error in metaphysical issues. In our opinion, this would be a way to develop a productive relationship between science and metaphysics. (shrink)

In this book authors study neutrosophic super matrices. The concept of neutrosophy or indeterminacy happens to be one the powerful tools used in applications like FCMs and NCMs where the expert seeks for a neutral solution. Thus this concept has lots of applications in fuzzy neutrosophic models like NRE, NAM etc. These concepts will also find applications in image processing where the expert seeks for a neutral solution.

Three separate churches erected in Constantinople were all dedicated to the wisdom of Christ and erected on the same site one after the other. These churches were built between 360 and 537 AD by three different emperors: Constantius II, Theodosius the Younger, and Justinian I. The first two churches were consumed in flames after relatively short lives, but the final and greatest church still stands today, despite a history of extensive damage. This final edifice is the main focus of this (...) paper, owing to its 1500 year longevity and unprecedented architecture. If the entire History of Justinian's church is to considered, it is inaccurate to refer to it as a “church,” because although it remained a church for the first 900 years after its audacious construction, it was later converted into a mosque. Today it is a museum, in remembrance of its long history. (24). (shrink)

Mindfulness training has been used to improve emotional wellbeing in early adolescents. However, little is known about treatment outcome moderators, or individual differences that may differentially impact responses to treatment. The current study focused on gender as a potential moderator for affective outcomes in response to school-based mindfulness training. Sixth grade students (N = 100) were randomly assigned to either the six weeks of mindfulness meditation or the active control group as part of a history class curriculum. Participants in the (...) mindfulness meditation group completed short mindfulness meditation sessions four to five times per week, in addition to didactic instruction (Asian history). The control group received matched experiential activity in addition to didactic instruction (African history) from the same teacher with no meditation component. Self-reported measures of emotional wellbeing/affect, mindfulness, and self-compassion were obtained at pre and post intervention. Meditators reported greater improvement in emotional wellbeing compared to those in the control group. Importantly, gender differences were detected, such that female meditators reported greater increases in positive affect compared to females in the control group, whereas male meditators and control males displayed equivalent gains. Uniquely among females but not males, increases in self-reported self-compassion were associated with improvements in affect. These findings support the efficacy of school-based mindfulness interventions, and interventions tailored to accommodate distinct developmental needs of female and male adolescents. (shrink)

In a series of recent publications, orofacial researchers have debated the question of how ‘bruxism’ should be defined for the purposes of accurate diagnosis and reliable clinical research. Following the principles of realism-based ontology, we performed an analysis of the arguments involved. This revealed that the disagreements rested primarily on inconsistent use of terms, so that issues of ontology were thus obfuscated by shortfalls in terminology. In this paper, we demonstrate how bruxism terminology can be improved by paying attention to (...) the relationships between (1) particulars and types, and (2) continuants and occurrents. (shrink)

This is a description and analysis of the intellectual culture of the eighteenth-century Church of England. Challenging conventional perceptions of the Church as an intellectually moribund institution, the study traces the influence of thinkers such as Locke, Newton, Burke, and Gibbon on theological debate in England during this period.

The current assessment of behaviors in the inventories to diagnose autism spectrum disorders (ASD) focus on observation and discrete categorizations. Behaviors require movements, yet measurements of physical movements are seldom included. Their inclusion however, could provide an objective characterization of behavior to help unveil interactions between the peripheral and the central nervous systems. Such interactions are critical for the development and maintenance of spontaneous autonomy, self-regulation and voluntary control. At present, current approaches cannot deal with the heterogeneous, dynamic and stochastic (...) nature of development. Accordingly, they leave no avenues for real-time or longitudinal assessments of change in a coping system continuously adapting and developing compensatory mechanisms. We offer a new unifying statistical framework to reveal re-afferent kinesthetic features of the individual with ASD. The new methodology is based on the non-stationary stochastic patterns of minute fluctuations (micro-movements) inherent to our natural actions. Such patterns of behavioral variability provide re-entrant sensory feedback contributing to the autonomous regulation and coordination of the motor output. From an early age, this feedback supports centrally driven volitional control and fluid, flexible transitions between intentional and spontaneous behaviors. We show that in ASD there is a disruption in the maturation of this form of proprioception. Despite this disturbance, each individual has unique adaptive compensatory capabilities that we can unveil and exploit to evoke faster and more accurate decisions. Measuring the kinesthetic re-afference in tandem with stimuli variations we can detect changes in their micro-movements indicative of a more predictive and reliable kinesthetic percept. Our methods address the heterogeneity of ASD with a personalized approach grounded in the inherent sensory-motor abilities that the individual has already developed. (shrink)

This paper provides a retrospective and prospective overview of TU Delft’s approach to engineering ethics education. For over twenty years, the Ethics and Philosophy of Technology Section at TU Delft has been at the forefront of engineering ethics education, offering education to a wide range of engineering and design students. The approach developed at TU Delft is deeply informed by the research of the Section, which is centered around Responsible Research and Innovation, Design for Values, and Risk Ethics. These theoretical (...) approaches are premised on the notion that technologies are inherently value-laden, and as such contain the possibility of fostering or hindering moral values. Each of these approaches encourages students to take a proactive attitude with respect to their projects and profession, thinking creatively about – and taking responsibility for – how to both prevent harm and do good via the technologies they help develop. To explain how this is put into practice, this paper sketches a brief history of ethics teaching at TU Delft, outlines current activities, and presents future plans for Bachelor and Master’s level engineering ethics education at TU Delft. (shrink)

Public discourse is often caustic and conflict-filled. This trend seems to be particularly evident when the content of such discourse is around moral issues (broadly defined) and when the discourse occurs on social media. Several explanatory mechanisms for such conflict have been explored in recent psychological and social-science literatures. The present work sought to examine a potentially novel explanatory mechanism defined in philosophical literature: Moral Grandstanding. According to philosophical accounts, Moral Grandstanding is the use of moral talk to seek social (...) status. For the present work, we conducted six studies, using two undergraduate samples (Study 1, N = 361; Study 2, N = 356); a sample matched to U.S. norms for age, gender, race, income, Census region (Study 3, N = 1,063); a YouGov sample matched to U.S. demographic norms (Study 4, N = 2,000); and a brief, one-month longitudinal study of Mechanical Turk workers in the U.S. (Study 5, Baseline N = 499, follow-up n = 296), and a large, one-week YouGov sample matched to U.S. demographic norms (Baseline N = 2,519, follow-up n = 1,776). Across studies, we found initial support for the validity of Moral Grandstanding as a construct. Specifically, moral grandstanding motivation was associated with status-seeking personality traits, as well as greater political and moral conflict in daily life. (shrink)

Howard Phillips Lovecraft’s work of fiction can roughly be grouped into three distinct categories, each evoking a singular extraordinary state of mind. Poe-inspired tales of the macabre such as “The Tomb” (1917) and “The Statement of Randolph Carter” (1919) produce terror because of the atmosphere they convey and because of the particular end the main characters meet. Lovecraft’s later “Yog-Sothothery” or work in the Cthulhu Mythos tradition, including his signature pieces of weird fiction “The Call of Cthulhu” (1926) and “The (...) Shadow over Innsmouth” (1931), inspires ‘horror’ because the life-worlds of the protagonists in these stories are utterly destroyed. However, the gentleman of Providence is also known for a different sort of fiction. His Dunsanian tales—among them short stories such as “The White Ship” (1919), “Celephaïs” (1920), and the three works“ The Silver Key” (1926), The Dream-Quest of Unknown Kadath (1926–27), and “Through the Gates of the Silver Key” (1932–33; with E. Hoffmann Price), centered on the exploits of Lovecraft’s recurring character and alter ego Randolph Carter—are epitomes to this feat. These prehistoric or dreamland tales do not inspire ‘terror’ or ‘horror’; rather, they predominately seek to evoke the extraordinary state of mind called ‘wonder. This article offers a preliminary exploration of Lovecraft’s relationship with wonder, highlights what wonder is, how Lovecraft was exposed to wonder at an early age, and argues that he developed a lifelong positive relationship with this particular state of mind. (shrink)

One of the vexed questions in the philosophy of wonder and indeed education is how to ensure that the next generation harbours a sense of wonder. Wonder is important, we think, because it encour- ages inquiry and keeps us as Albert Einstein would argue from ‘being as good as dead’ or ‘snuffed-out candles’ (Einstein 1949, 5). But how is an educator to install, bring to life, or otherwise encourage a sense of wonder in his or her stu- dents? Biologist Rachel (...) Carson suggests that exploring nature and specifically undertaking walks along the rocky coast of Maine would keep alive a person’s inborn sense of wonder (Carson 1984). Philosopher Jesse Prinz thinks that exposure to art will encourage wonderment because artworks, as he puts it, are “inventions for feeding the appetite that wonder excites in us” (Prinz 2013). Weird fiction (a subgenre of speculative fiction) – and in particular the work of one of its greatest exponents, the early-20th-century American author How- ard Phillips Lovecraft – is likewise a catalyst for wonder. The reason behind this is that Lovecraft’s ‘wonder-stories’ are densely packed with wonder per design; and in support of this claim I shall in what is to come 1) provide a brief introduction to Lovecraft and weird fiction; 2) present a working definition of wonder; and 3) clarify what is meant by something being ‘densely packed with wonder’ via bringing to the fore evidence of Lovecraft’s literary wonder- mongery. The paper ends with some reflections on the notion of ‘dark wonder’, why this peculiar label might be suitable for the kind of wonder we find in Lovecraft’s work, and why exposure to ‘dark wonder’ can be edifying, and in that sense educational. (shrink)

Automated reasoning about uncertain knowledge has many applications. One difficulty when developing such systems is the lack of a completely satisfactory integration of logic and probability. We address this problem directly. Expressive languages like higher-order logic are ideally suited for representing and reasoning about structured knowledge. Uncertain knowledge can be modeled by using graded probabilities rather than binary truth-values. The main technical problem studied in this paper is the following: Given a set of sentences, each having some probability of being (...) true, what probability should be ascribed to other (query) sentences? A natural wish-list, among others, is that the probability distribution (i) is consistent with the knowledge base, (ii) allows for a consistent inference procedure and in particular (iii) reduces to deductive logic in the limit of probabilities being 0 and 1, (iv) allows (Bayesian) inductive reasoning and (v) learning in the limit and in particular (vi) allows confirmation of universally quantified hypotheses/sentences. We translate this wish-list into technical requirements for a prior probability and show that probabilities satisfying all our criteria exist. We also give explicit constructions and several general characterizations of probabilities that satisfy some or all of the criteria and various (counter) examples. We also derive necessary and sufficient conditions for extending beliefs about finitely many sentences to suitable probabilities over all sentences, and in particular least dogmatic or least biased ones. We conclude with a brief outlook on how the developed theory might be used and approximated in autonomous reasoning agents. Our theory is a step towards a globally consistent and empirically satisfactory unification of probability and logic. (shrink)

Vigorous debate over the moral propriety of cognitive enhancement exists, but the views of the public have been largely absent from the discussion. To address this gap in our knowledge, four experiments were carried out with contrastive vignettes in order to obtain quantitative data on public attitudes towards cognitive enhancement. The data collected suggest that the public is sensitive to and capable of understanding the four cardinal concerns identified by neuroethicists, and tend to cautiously accept cognitive enhancement even as they (...) recognize its potential perils. The public is biopolitically moderate, endorses both meritocratic principles and the intrinsic value of hard work, and appears to be sensitive to the salient moral issues raised in the debate. Taken together, these data suggest that public attitudes toward enhancement are sufficiently sophisticated to merit inclusion in policy deliberations, especially if we seek to align public sentiment and policy. (shrink)

Achieving space situational awareness requires, at a minimum, the identification, characterization, and tracking of space objects. Leveraging the resultant space object data for purposes such as hostile threat assessment, object identification, and conjunction assessment presents major challenges. This is in part because in characterizing space objects we reference a variety of identifiers, components, subsystems, capabilities, vulnerabilities, origins, missions, orbital elements, patterns of life, operational processes, operational statuses, and so forth, which tend to be defined in highly heterogeneous and sometimes inconsistent (...) ways. The Space Domain Ontologies are designed to provide a consensus-based realist framework for formulating such characterizations in a way that is both consistent and computable. Space object data are aligned with classes and relations in a suite of ontologies built around the existing Space Object Ontology. They are stored in a dynamically updated Resource Description Framework triple store, which can be queried to support space situational awareness and the needs of spacecraft operators and analysts. This paper provides an overview of the Space Domain Ontologies and their development and use. It presents the motivation for and advantages of the Space Domain Ontologies, including the benefits they provide for enhancing and maintaining long-term space situational awareness. (shrink)

Functional diversity holds the promise of understanding ecosystems in ways unattainable by taxonomic diversity studies. Underlying this promise is the intuition that investigating the diversity of what organisms actually do—i.e. their functional traits—within ecosystems will generate more reliable insights into the ways these ecosystems behave, compared to considering only species diversity. But this promise also rests on several conceptual and methodological—i.e. epistemic—assumptions that cut across various theories and domains of ecology. These assumptions should be clearly addressed, notably for the sake (...) of an effective comparison and integration across domains, and for assessing whether or not to use functional diversity approaches for developing ecological management strategies. The objective of this contribution is to identify and critically analyze the most salient of these assumptions. To this aim, we provide an “epistemic roadmap” that pinpoints these assumptions along a set of historical, conceptual, empirical, theoretical, and normative dimensions. (shrink)

Betrachtet man den Gebrauch der Worte ‘Moral’ und ‘Vernunft’ etwas genauer, so stellt man fest, dass nicht klar ist, was sie bezeichnen bzw. wie Moral und Vernunft zusammenhängen. In dem Buch ‘Rationalität in der Angewandten Ethik’, in dem sich verschiedene Autoren die Aufgabe gestellt haben, diese Umstände in das Licht der Betrachtung zu rücken, finden wir Fragen darüber, wie “Moral”, “Angewandte Ethik” und “Vernunft” (auch in der Anwendung) zu verstehen und zu vereinen sind.

The fructose 6-phosphate (Fru-6P) saturation curve for phosphofructokinase (PFK) from E. coli is sigmoidal in the presence of saturating MgATP levels, while the corresponding curve for B. stearothermophilus PFK is essentially hyperbolic. Sigmoidality can be due to apparent cooperativity arising from the kinetic mechanism of an enzyme. We have determined the kinetic mechanism of B. stearothermophilus PFK (BsPFK). BsPFK was found to obey a non rapid-equilibrium random mechanism similar to the one E. coli PFK (EcPFK) follows. Substrate inhibition by MgATP (...) was observed. We propose that substrates bind to BsPFK through two alternative pathways, one of which is slower. The substrate inhibition arises in part from reaction flux through the slower pathway. Although EcPFK and BsPFK obey similar kinetic mechanisms, they are inhibited differently by MgATP: EcPFK is profoundly inhibited, BsPFK only weakly. The structural basis for this difference could be closure of the active site via a conformational transition that occurs in EcPFK, but not BsPFK. To investigate the importance of this transition for MgATP inhibition of EcPFK, we have constructed a chimeric enzyme (ChiPFK) that contains the "rigid" ATP-binding domain of BsPFK grafted onto the remainder of the EcPFK subunit. Our results indicate that ChiPFK is locked in an "open" structure resembling the activated form of EcPFK. It is insensitive to heterotropic regulation. Nevertheless, ChiPFK exhibits residual cooperativity. Possible explanations for the cooperativity are discussed. The 6F loop is proposed to be important in PFK allosteric behavior. Residues along the loop are largely conserved between BsPFK and EcPFK, except for 161, which is a glutamate in BsPFK, and a glutamine in EcPFK. Using site-directed mutagenesis, Glu 161 of BsPFK has been changed to glutamine and alanine. Similarly, Gin 161 of EcPFK has been changed to glutamate, arginine and alanine. Of the five mutants, one, QA161, was particularly interesting. Though activated normally by GDP, it was completely insensitive to PEP inhibition. This indicates that the hydrogen-bonding ability of residue 161 is critical for PEP inhibition of EcPFK, and that GDP activation and PEP inhibition follow different structural pathways. (shrink)

We introduce and consider the inner-model reflection principle, which asserts that whenever a statement \varphi(a) in the first-order language of set theory is true in the set-theoretic universe V, then it is also true in a proper inner model W \subset A. A stronger principle, the ground-model reflection principle, asserts that any such \varphi(a) true in V is also true in some non-trivial ground model of the universe with respect to set forcing. These principles each express a form of width (...) reflection in contrast to the usual height reflection of the Lévy–Montague reflection theorem. They are each equiconsistent with ZFC and indeed \Pi_2-conservative over ZFC, being forceable by class forcing while preserving any desired rank-initial segment of the universe. Furthermore, the inner-model reflection principle is a consequence of the existence of sufficient large cardinals, and lightface formulations of the reflection principles follow from the maximality principle MP and from the inner-model hypothesis IMH. We also consider some questions concerning the expressibility of the principles. (shrink)

Wrong beliefs, known by some as ‘alternative facts’, have proliferated lately in important areas of human life, including social, political, and public health domains. This can be and has been damaging. This brief article proposes an epistemological category classification of these wrong beliefs, with the following mappings: a) ‘No-Information’ marked by willful blindness produces ‘Empty Beliefs’; b) ‘Mis-Information’ yields ‘Mis(taken) Beliefs’; and c) ‘Dis-Information’ predicated on blatant distortions produces ‘Dis(torted) Beliefs’. This simple classification system, is perhaps epistemologically satisfying, and moreover (...) could have positive policy implications. (shrink)

Few of Kant’s doctrines are as difficult to understand as that of self-affection. Its brief career in the published literature consists principally in its unheralded introduction in the Transcendental Aesthetic and unexpected re-appearance at a key moment in the Deduction chapter in the B edition of the first Critique. Kant’s commentators, confronted with the difficulty of this doctrine, have naturally resorted to various strategies of clarification, ranging from distinguishing between empirical and transcendental self-affection, divorcing self-affection from the claims of self-knowledge (...) with which Kant explicitly connects it, and, perhaps least justified of all, ignoring the doctrine altogether. Yet the connection between self-affection and central Critical doctrines (such as the transcendental synthesis of the imagination) marks all of these strategies as last resorts. In this paper, I seek to provide a clearer outline of the constellation of those issues which inform Kant’s discussion of self-affection. More particularly, I intend to explain the crucial role played by self-affection in the account of the transcendental conditions of perception provided late in the B Deduction. (shrink)

This is the second part of a two-part series on the logic of hyperlogic, a formal system for regimenting metalogical claims in the object language (even within embedded environments). Part A provided a minimal logic for hyperlogic that is sound and complete over the class of all models. In this part, we extend these completeness results to stronger logics that are sound and complete over restricted classes of models. We also investigate the logic of hyperlogic when the language is enriched (...) with hyperintensional operators such as counterfactual conditionals and belief operators. (shrink)

Recent work has defended “Euclidean” theories of set size, in which Cantor’s Principle (two sets have equally many elements if and only if there is a one-to-one correspondence between them) is abandoned in favor of the Part-Whole Principle (if A is a proper subset of B then A is smaller than B). It has also been suggested that Gödel’s argument for the unique correctness of Cantor’s Principle is inadequate. Here we see from simple examples, not that Euclidean theories of set (...) size are wrong, but that they must be either very weak and narrow or largely arbitrary and misleading. (shrink)

A review of James Skillen's book exploring the character of Christian democracy, what it is, what it has become, what it should be.

There is no uniquely standard concept of an effectively decidable set of real numbers or real n-tuples. Here we consider three notions: decidability up to measure zero [M.W. Parker, Undecidability in Rn: Riddled basins, the KAM tori, and the stability of the solar system, Phil. Sci. 70(2) (2003) 359–382], which we abbreviate d.m.z.; recursive approximability [or r.a.; K.-I. Ko, Complexity Theory of Real Functions, Birkhäuser, Boston, 1991]; and decidability ignoring boundaries [d.i.b.; W.C. Myrvold, The decision problem for entanglement, in: R.S. (...) Cohen et al. (Eds.), Potentiality, Entanglement, and Passion-at-a-Distance: Quantum Mechanical Studies fo Abner Shimony, Vol. 2, Kluwer Academic Publishers, Great Britain, 1997, pp. 177–190]. Unlike some others in the literature, these notions apply not only to certain nice sets, but to general sets in Rn and other appropriate spaces. We consider some motivations for these concepts and the logical relations between them. It has been argued that d.m.z. is especially appropriate for physical applications, and on Rn with the standard measure, it is strictly stronger than r.a. [M.W. Parker, Undecidability in Rn: Riddled basins, the KAM tori, and the stability of the solar system, Phil. Sci. 70(2) (2003) 359–382]. Here we show that this is the only implication that holds among our three decidabilities in that setting. Under arbitrary measures, even this implication fails. Yet for intervals of non-zero length, and more generally, convex sets of non-zero measure, the three concepts are equivalent. (shrink)

Ang papel ay paglalagom ng itinuturing na pinakamahalagang yugto ng buhay ni José Rizal—ang kanyang pagkakatapon sa Dapitan, sa lente ng konseptong “bagani” ng ating mga ninuno. Sa pagbanggit sa lang nauna nang pag-aaral ukol kay Rizal, ipapakitang kung papaanong ang yugto sa Dapitan ay ang katuparan ng kanyang mga layunin sa La Liga Filipina, na kanyang isinabuhay kasama ang bayan. Sa lente ng kasalukuyang pandemyang COVID 19, makikita natin na tila naranasan din ni Rizal sa kanyang pagkakatapon ang (...) ilang bagay na ating dinaranas ngayon, na tila siya isang frontliner na nasa lockdown, inilagay sa kuwarentena, nag-homeschooling, nagkaroon ng lockdown sickness at namahagi ng ayudang pangkabuhayan sa mga mamamayan ng isang natutulog na bayan upang ito ay sumiglang muli. Nawa ay maging inspirasyon sa bayan na anuman ang hamon at mga balakid, walang makapipigil sa isang Pilipino na magsilbi sa bayan gamit ang kanyang mga talento at manatiling liwanag ng katotohanan at kaalaman. (shrink)

According to a common objection to epistemological naturalism, no empirical, scientific theory of knowledge can be normative in the way epistemological theories need to be. In response, such naturalists as W.V. Quine have claimed naturalized epistemology can be normative by emulating engineering disciplines and addressing the relations of causal efficacy between our cognitive means and ends. This paper evaluates that "engineering reply" and finds it a mixed success. Based on consideration of what it might mean to call a theory "normative," (...) seven versions of the normativity objection to epistemological naturalism are formulated. The engineering reply alone is sufficient to answer only the four least sophisticated versions. To answer the others, naturalists must draw on more resources than their engineering reply alone provides. (shrink)

Karl Popper discovered in 1938 that the unconditional probability of a conditional of the form ‘If A, then B’ normally exceeds the conditional probability of B given A, provided that ‘If A, then B’ is taken to mean the same as ‘Not (A and not B)’. So it was clear (but presumably only to him at that time) that the conditional probability of B given A cannot be reduced to the unconditional probability of the material conditional ‘If A, then B’. (...) I describe how this insight was developed in Popper’s writings and I add to this historical study a logical one, in which I compare laws of excess in Kolmogorov probability theory with laws of excess in Popper probability theory. (shrink)